I saw that tool (pixatool), played a little with demo, and in this form in my opinion it's mostly for textures, static images and some artworks, better solution would be this Blender plugin/shader as it looks closer to real pixel-art. But thinking about real pixel-art for games I rather think about 32x32 tileset, or 64x32 character or something little larger and to getting readable and nice looking sprite with this tools could be hard to achieve, as they prefer larger image outputs, something that would fit as cover, menu background, character portraits... On other hand they would do great job in full-hd/4k pseudo pixel-art games so of course there is a field to show off for them. Best example for pixatool would be some wolf3d clone, this app could be use to do 'create' all textures.